CYP1A2 11 Allele
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CYP1A2 11 Allele Definition
Human CYP1A2*11 allele is located within 15q24 and is approximately 8 kb in length. This allele, a variant form of the CYP1A2 wild-type allele, encodes cytochrome P450 1A2*11 protein. The CYP1A2*11 allele exhibits a clinically-relevant SNP (g.558C>A) in exon 2 that results in a F186L coding change. This alteration in protein sequence severely decreases the enzymatic activity of the cytochrome P450 1A2*11 protein.
CYP1A2 11 Allele Synonyms
CYP1A2*11 Allele, CYP1A2*11, CYP1A2, F186L, CYP1A2, g.558C>A, Cytochrome P450, Family 1, Subfamily A, Polypeptide 2*11 Allele
Terms in CYP1A2 11 Allele category
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