CYP2C19 8 Allele
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CYP2C19 8 Allele Definition
Human CYP2C19*8 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19 wild-type allele, encodes cytochrome P450 2C19*8 protein. The CYP2C19*8 allele exhibits a clinically-relevant SNP (c.358T>C) in exon 3 that results in a W120R coding change. This alteration in protein sequence severely decreases the enzymatic activity of the cytochrome P450 2C19*8 protein.
CYP2C19 8 Allele Synonyms
CYP2C19*8 Allele, CYP2C19*8, CYP2C19, W120R, CYP2C19, c.358T>C, Cytochrome P450, Family 2, Subfamily C, Polypeptide 19*8 Allele
Terms in CYP2C19 8 Allele category
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