CYP2C9 11 Allele
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CYP2C9 Gene -> CYP2C9 11 Allele
CYP2C9 11 Allele Definition
Human CYP2C9*11 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9 wild-type allele, encodes cytochrome P450 2C9*11 protein. The CYP2C9*11 allele exhibits a clinically-relevant SNP (c.1003C>T) in exon 7 that results in a R335W coding change. This alteration in protein sequence severely decreases the enzymatic activity of the cytochrome P450 2C9*11 protein.
CYP2C9 11 Allele Synonyms
CYP2C9*11 Allele, CYP2C9*11, CYP2C9, R335W, CYP2C9, c.1003C>T, Cytochrome P450, Family 2, Subfamily C, Polypeptide 9*11 Allele
Terms in CYP2C9 11 Allele category
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