CYP3A7 2 Allele
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CYP3A7 Gene -> CYP3A7 2 Allele
CYP3A7 2 Allele Definition
Human CYP3A7*2 allele is located within 7q21-q22.1 and is approximately 30 kb in length. This allele, a variant form of the human CYP3A7 wild-type allele, encodes cytochrome P450 3A7*2 protein. This allele exhibits a clinically-relevant SNP (c.1226C>G) in exon 11 that results in a T409R coding change. This alteration in protein sequence increases the enzymatic activity of the cytochrome P450 3A7*2 protein.
CYP3A7 2 Allele Synonyms
CYP3A7*2 Allele, CYP3A7*2, CYP3A7, T409R, CYP3A7, c.1226C>G, Cytochrome P450, Family 3, Subfamily A, Polypeptide7*2 Allele
Terms in CYP3A7 2 Allele category
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