Calcineurin-A Beta
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Calcineurin-A Beta Definition
Encoded by human PPP3CB Gene (PPP Phosphatase/PP-2B Family), 510-aa Calcineurin A Beta is a brain calmodulin-binding catalytic subunit of ubiquitous heterodimeric Ca(2+)/calmodulin-regulated protein phosphatase Calcineurin. Calcineurin catalytic subunits are derived from alternatively spliced highly conserved PPP3CA, PPP3CB, PPP3CC genes. Activated PPP3CB appears involved in dopaminergic signal transduction and in some glutamatergic NMDA receptor-dependent synaptic plasticity. (NCI)
Calcineurin-A Beta Synonyms
Calcineurin A Beta, CAM-PRP Catalytic Subunit, Calmodulin-Dependent Calcineurin A Subunit Beta Isoform, PPP3CB, Protein Phosphatase 3 Catalytic Subunit Beta Isoform, Serine/Threonine Protein Phosphatase 2B Catalytic Subunit Beta Isoform
Terms in Calcineurin-A Beta category
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