Cancer Terms

Calpain

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Hydrolase -> Protease -> Cysteine Proteinase -> Calpain

Calpain Definition

A class of calcium-dependent thiol-proteases that proteolytically cleave a wide variety of cytoskeletal, membrane-associated, and regulatory proteins. There are two main isoforms of the protein, which differ in their calcium requirement for activation. These enzymes have been linked to both acute and chronic neurodegenerative processes, such as: ischemia, trauma, and Alzheimer's disease.

Calpain Synonyms

Calpain, Papain-Like Cysteine Protease

Terms in Calpain category



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