Carbenicillin
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Carbenicillin Definition
A broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Carbenicillin acylates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis.
Carbenicillin Synonyms
Carbenicillin, CARBENICILLIN, Geopen, Pyopen
Terms in Carbenicillin category
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