Cardiotrophin-1
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Cardiotrophin-1 Definition
Cardiotrophin 1 was cloned via its ability to potently induce cardiac myocyte hypertrophy in vitro. It is a member of the family of cytokines that includes leukemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), oncostatin M (OSM), and interleukin 6 (IL6). Several members of this family that are known to signal through the transmembrane protein gp130 stimulate cardiac myocyte hypertrophy, like cardiotrophin 1, suggesting that the gp130 signaling pathway may play a role in cardiac hypertrophy. (from OMIM)
Cardiotrophin-1 Synonyms
Cardiotrophin 1, CTF1, Cardiophin 1
Terms in Cardiotrophin-1 category
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