Cancer Terms

Caspase Activation

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Caspase Activation Definition

Caspase Activation involves induction of the activity of intracellular cysteine endopeptidase family members kept inactive by mitochondrial surface proteins (BcL-2 Family) and involved in initial signaling and downstream proteolytic cleavages (at P1 aspartic acids) in inflammation and apoptotic cell death when signals block BcL-2 function and activators initiate caspase cascades.

Caspase Activation Synonyms

Caspase Activation

Terms in Caspase Activation category



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