Cancer Terms

Cationic Liposome-Encapsulated Paclitaxel

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Antimitotic Agent -> Tubulin Binding Agent -> Taxane-Site Binding Agent -> Paclitaxel Preparation -> Cationic Liposome-Encapsulated Paclitaxel

Cationic Liposome-Encapsulated Paclitaxel Definition

A cationic liposome preparation of paclitaxel with antineoplastic activity. Paclitaxel, the active ingredient in cationic liposome-encapsulated paclitaxel, binds to tubulin and inhibits the disassembly of microtubules, resulting in the inhibition of mitosis and cellular proliferation, and apoptosis. Cationic liposome encapsulation of paclitaxel allows the delivery of high doses of paclitaxel to target tissues while minimizing systemic toxicity. Tumor endothelial cells may preferentially bind and internalize cationic liposomes.

Cationic Liposome-Encapsulated Paclitaxel Synonyms

Cationic Liposome-Encapsulated Paclitaxel, EndoTAG-1, LipoPac, MBT-0206

Terms in Cationic Liposome-Encapsulated Paclitaxel category



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