Cancer Terms

Ceftobiprole Medocaril

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Anti-Infective Agent -> Antibiotic -> Cephalosporin Antibiotic -> Ceftobiprole Medocaril

Ceftobiprole Medocaril Definition

A water-soluble prodrug of ceftobiprole, a pyrrolidinone cephalosporin antibiotic, with bactericidal activity. Ceftobiprole binds to and inactivates penicillin-binding proteins (PBPs), enzymes involved in the terminal stages of bacterial cell wall assembly and cell wall reshaping during bacterial growth and division. This agent exhibits a broad spectrum of activity against gram-negative and gram-positive pathogens including methicillin-resistant S. aureus (MRSA), vancomycin-intermediate S. aureus (VISA) and vancomycin-resistant S. aureus (VRSA). Ceftobiprole is refractory to hydrolysis by class A and class C lactamases.

Ceftobiprole Medocaril Synonyms

Ceftobiprole Medocaril, BAL5788, CEFTOBIPROLE MEDOCARIL, JNJ30982081, RO 65-5788

Terms in Ceftobiprole Medocaril category



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