Cancer Terms

Chloride Anion Exchanger

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Ligand Binding Protein -> Transport Protein -> Ion Channel Protein -> Chloride Anion Exchanger

Chloride Anion Exchanger Definition

Encoded by human SLC26A3 Gene (SLC26A/SulP Transporter Family), 764-aa 85-kDa Chloride Anion Exchanger is a sulfate/chloride/bicarbonate transmembrane glycoprotein exchange transporter containing 1 STAS domain and localized in lower intestinal columnar epithelial apical membranes and some goblet cells. Involved in absorbtion, SLC26A3 mediates electrolyte and fluid absorption. Defects in SLC26A3 are the cause of congenital chloride diarrhea (CLD). (NCI)

Chloride Anion Exchanger Synonyms

Chloride Anion Exchanger, CLD, DRA Protein, Down-Regulated in Adenoma Protein, Solute Carrier Family 26 Member 3

Terms in Chloride Anion Exchanger category



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