Cancer Terms

Cilengitide

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Angiogenesis Inhibitor -> Endothelial-Specific Integrin-Survival Signaling Inhibitor -> Cilengitide

Cilengitide Definition

A cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. (NCI04)

Cilengitide Synonyms

Cilengitide, EMD 121974, EMD-121974, cyclo(L-arginylglycyl-L-a-aspartyl-D-phenylalanyl-N-methyl-L-valyl)

Terms in Cilengitide category



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