Clinical Endpoint

Cancer Terms -> Diagnostic or Prognostic Factor -> Biomarker -> End Point -> Clinical Endpoint

Clinical Endpoint Definition

A characteristic or variable that reflects how a patient feels, functions, or survives. Clinical endpoints are distinct measurements or analyses of disease characteristics observed in a study or a clinical trial that reflect the effect of a therapeutic intervention. Clinical endpoints are the most credible characteristics used in the assessment of the benefits and risks of a therapeutic intervention in randomized clinical trials. Biomarkers Definitions Working Group. Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework. Clin Pharm Ther 69 (3): 89-95, 2001.