Cancer Terms

Clomesone

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Alkylating Agent -> Antineoplastic Alkylating Agent -> Alkylsulfonate Compound -> Clomesone

Clomesone Definition

The 2-chloroethyl ester of (methylsulfonyl) methanesulfonic acid with potential antineoplastic effects. Acting as a chloroethylating agent, clomesone induces the formation of DNA interstrand crosslinks in some cell lines, and exhibits antitumor activity in some animal models. Alkylating agents exert cytotoxic and, in some cases, chemotherapeutic effects by transferring alkyl groups to DNA, thereby damaging DNA and interfering with DNA synthesis and cell division. (NCI04)

Clomesone Synonyms

Clomesone

Terms in Clomesone category



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