Collagen IV Alpha-6

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Structural Protein -> Extracellular Matrix Protein -> Collagen -> Collagen IV Alpha-6

Collagen IV Alpha-6 Definition

Collagen IV (Alpha 6), encoded by the human COL4A6 gene, is a subunit of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene. (From LocusLink and NCI)

Collagen IV Alpha-6 Synonyms

Collagen IV (Alpha 6), COL4A6, COL4A6 Protein

Terms in Collagen IV Alpha-6 category

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