Cancer Terms

Complement-Dependent Cytotoxicity

Cancer Terms -> Biological Process -> Cellular Process -> Cell Viability Process -> Cell Death -> Mechanism of Cell Death -> Cytolysis Induction -> Complement-Dependent Cytotoxicity

Complement-Dependent Cytotoxicity Definition

Activated by cell-surface bound antibody, by immune complexes, or by microbial membrane carbohydrate, Complement-Dependent Cytotoxicity involves complex cascades (classical or properdin pathway) of sequentially interacting serum proteins (some serine proteases), their receptors, and related regulatory proteins that generate Membrane Attack Complex, which creates target cell pores and lysis.

Complement-Dependent Cytotoxicity Synonyms

Complement-Dependent Cytotoxicity

Terms in Complement-Dependent Cytotoxicity category



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