Cancer Terms

Copper Cu 61-ATSM

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Radiopharmaceutical Compound -> Radioconjugate -> Copper Cu 61-ATSM

Copper Cu 61-ATSM Definition

A lipophilic copper(II)bis(thiosemicarbazone) labeled with the positron-emitting isotope (61)Cu with hypoxia-selective and radioisotopic activities. With a high membrane permeability and redox potential, (61)Cu-ATSM easily enters and selectively resides in hypoxic cells. The extent of (61)Cu-ATSM retention in tissue is inversely related to the state of tissue oxygenation allowing the quantitation of tissue hypoxia with positron emission tomography (PET).

Copper Cu 61-ATSM Synonyms

Copper Cu 61-ATSM

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