Core-Binding Factor

Cancer Terms -> Gene Product -> Protein or Riboprotein Complex -> Core-Binding Factor

Core-Binding Factor Definition

CBF is an alpha/beta heterodimeric transcription factor involved in the transcriptional regulation of several genes important in hematopoiesis. The CBFalpha subunit binds directly to the enhancer core DNA sequence on target genes, whereas the beta subunit does not bind the DNA directly but increases the affinity and stabilizes the binding of the alpha subunit to the DNA.

Core-Binding Factor Synonyms

Core-Binding Factor, CBF

Core-Binding Factor

Core-Binding Factor Definition

Core-Binding Factor Synonyms

Terms in Core-Binding Factor category