Cullin Family Gene

Cancer Terms -> Gene -> Regulatory Gene -> Cullin Family Gene

Cullin Family Gene Definition

Cullin Family Genes encode Cullin Family Proteins, which are components of SCF ubiquitin ligase complexes or E3 ubiquitin ligase complexes with elongin BC complexes and other factors, involved in ubiquitination and proteasomal degradation of target cell cycle, signal transduction, and transcription proteins. Cullins may act in these multisubunit complexes as a scaffold for substrates and ubiquitin-conjugating enzymes and interact with RBX1, RNF7, CYCE, and/or TIP120A/CAND1. (NCI)

Cullin Family Gene Synonyms

Cullin Family Gene

Terms in Cullin Family Gene category

CUL1 Gene
CUL2 Gene
CUL3 Gene
CUL4A Gene
CUL5 Gene