Cancer Terms

Cyclin-Dependent Kinase Inhibitor-1A

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Cyclin-Dependent Kinase Inhibitor-1A Definition

May mediate p53 inhibition of cell proliferation in response to DNA damage. CIP1 appears to be a tight-binding inhibitor of CDKs. CDKN1A expression is tightly regulated by p53 and IFN-Beta. The CIP1 N-terminus is similar to KIP1. CIP1 is truncated by CASP3 in apoptosis. (from SWISS-PROT P38936, OMIM 116899, and NCI)

Cyclin-Dependent Kinase Inhibitor-1A Synonyms

Cyclin-Dependent Kinase Inhibitor 1A, CDK-Interacting Protein 1, CDKN1A, CDKN1A Protein, CIP-1 Protein, MDA 6, WAF-1 Protein, p21

Terms in Cyclin-Dependent Kinase Inhibitor-1A category



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