Cancer Terms

Cyclin-Dependent Kinase Inhibitor-1C

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Cyclin-Dependent Kinase Inhibitor-1C Definition

A negative regulator of cell proliferation, KIP2 is a tight-binding inhibitor of the G1 Cyclin E-CDK2, Cyclin D2-CDK4, and Cyclin A-CDK2 complexes, and also inhibits mitotic Cyclin B-CDC2. The N-terminal CDK inhibitory domain is similar to p21(CIP1). (from SWISS-PROT P49918, OMIM 600856, and NCI)

Cyclin-Dependent Kinase Inhibitor-1C Synonyms

Cyclin-Dependent Kinase Inhibitor 1C, Beckwith-Wiedemann Syndrome Protein, CDKN1C, CDKN1C Protein, Cyclin-Dependent Kinase Inhibitor p57, KIP2 Protein, p57-KIP2 Protein

Terms in Cyclin-Dependent Kinase Inhibitor-1C category



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