Cyclin-Dependent Kinase Inhibitor-2A

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Cyclin-Dependent Kinase Inhibitor-2A Definition

Product of the CDKN2A gene. Also called p16(INK4). A tumor suppressor and a negative regulator of progression through G1. p16(INK4) interacts with CDK4/CDK6, inhibiting their interaction with Cyclin D and the phosphorylation of RB.

Cyclin-Dependent Kinase Inhibitor-2A Synonyms

Cyclin-Dependent Kinase Inhibitor 2A, CDK4 Inhibitor, CDK4I, CDKN2A, CDKN2A Protein, Cell Cycle Negative Regulator Beta, Cyclin-Dependent Kinase Inhibitor p12, Cyclin-Dependent Kinase Inhibitor p16, MTS1, MTS1 Protein, Multiple Tumor Suppressor 1, P16(INK4A), p14(ARF), p16(INK4), p16-INK4, p16-INK4a, p19(ARF)

Terms in Cyclin-Dependent Kinase Inhibitor-2A category

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