Cancer Terms

Cyclin-Dependent Kinase-1

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Cell Cycle Protein -> Cyclin-Dependent Kinase -> Cyclin-Dependent Kinase-1

Cyclin-Dependent Kinase-1 Definition

A serine/threonine protein kinase subunit of the M-phase promoting factor complex, required for entry into S-phase and mitosis. A member of the CDC2/CDKX subfamily, p34(cdc2) forms a complex with a Cyclin, and phosphorylates RNA Polymerase II. CDC2 gene expression is transcriptionally regulated and phosphorylation regulates cdc2 activity. (from SWISS-PROT P06493, OMIM 116940, and NCI)

Cyclin-Dependent Kinase-1 Synonyms

Cyclin-Dependent Kinase 1, CDC2, CDK1, Cell Cycle Controller cdc2, Cell Division Control Protein 2 Homolog, Cell Division Cycle 2, Cell Division Cycle 2 Protein, p34 Protein Kinase, p34(CDC2), p34CDC2

Terms in Cyclin-Dependent Kinase-1 category



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