Cyclin-Dependent Kinase-10

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Cell Cycle Protein -> Cyclin-Dependent Kinase -> Cyclin-Dependent Kinase-10

Cyclin-Dependent Kinase-10 Definition

Cyclin-Dependent Kinase 10, encoded by the CDK10 gene, is a protein that belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members bind to cyclin to form active holoenzymes that play a pivotal role in the regulation of the eukaryotic cell cycle and are known to be essential for cell cycle progression. This kinase has been shown to play roles in cellular proliferation and its function is limited to cell cycle G2-M phase. A variety of different transcripts exist, resulting from cryptic splice sites, exon skipping, insertion of intronic sequences, and exon scrambling. The splicing of this gene is complex. At least three alternatively spliced variants of this gene exist, one of which contains multiple non-ATG translation initiation sites. (From LocusLink, OMIM and NCI)

Cyclin-Dependent Kinase-10 Synonyms

Cyclin-Dependent Kinase 10, CDK10, CDK10 Protein, Cell Division Protein Kinase 10, EC 2.7.1.-, PISSLRE Protein, Serine/Threonine-Protein Kinase PISSLRE

Cyclin-Dependent Kinase-10

Cyclin-Dependent Kinase-10 Definition

Cyclin-Dependent Kinase-10 Synonyms

Terms in Cyclin-Dependent Kinase-10 category