Cancer Terms

Cyproheptadine Hydrochloride

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Biological Response Modifier -> Histamine-1 Receptor Antagonist -> Cyproheptadine Hydrochloride

Cyproheptadine Hydrochloride Definition

The hydrochloride salt of a synthetic methyl-piperidine derivative with antihistaminic and anti-serotoninergic properties. Cyproheptadine competes with free histamine (HA) for binding at HA-receptor sites, thereby competitively antagonizing histamine stimulation of HA-receptors in the gastrointestinal tract, large blood vessels, and bronchial smooth muscle. This agent also competes with free serotonin for binding at serotonin receptor sites. Cyproheptadine exhibits anticholinergic and sedative properties and has been shown to stimulate appetite and weight gain. (NCI04)

Cyproheptadine Hydrochloride Synonyms

Cyproheptadine Hydrochloride, CYPROHEPTADINE HYDROCHLORIDE, Periactin

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