Cancer Terms

Cytochrome-P450-2C9

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Oxidoreductase -> Cytochrome -> Cytochrome-P450 -> Cytochrome-P450-2C9

Cytochrome-P450-2C9 Definition

Induced by rifampin and expressed in liver by polymorphic human CYP2C9 Gene (CYP450 Family), 490-aa 56-kD Cytochrome P450 2C9 localizes to the endoplasmic reticulum membrane and oxidizes steroids, fatty acids, and xenobiotics in drug metabolism and in the synthesis of cholesterol, steroids and other lipids.

Cytochrome-P450-2C9 Synonyms

Cytochrome P450 2C9, CYP2C9, CYPIIC9, Cytochrome P450, Family 2, Subfamily C, Polypeptide 9, Cytochrome P450, Subfamily IIC (Mephenytoin 4-Hydroxylase), Polypeptide 10, Cytochrome P450, Subfamily IIC (Mephenytoin 4-Hydroxylase), Polypeptide 9, EC 1.14.14.1, Flavoprotein-Linked Monooxygenase, Mephenytoin 4-Hydroxylase, Microsomal Monooxygenase, P-450MP, P450 MP-4, P450 PB-1, S-Mephenytoin 4-Hydroxylase, Xenobiotic Monooxygenase

Terms in Cytochrome-P450-2C9 category



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