Cancer Terms

DAB2 wt Allele

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DAB2 wt Allele Definition

Human DAB2 wild-type allele is located within 5p13 and is approximately 52 kb in length. This allele, which encodes disabled homolog 2 protein, plays a role in the inhibition of cell proliferation. Down-regulation or complete loss of DAB2 gene expression is associated with certain cancers such as breast cancer and ovarian epithelial carcinomas.

DAB2 wt Allele Synonyms

DAB2 wt Allele, DOC-2, DOC2, Disabled Homolog 2, Mitogen-Responsive Phosphoprotein (Drosophila) wt Allele

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