DCC Protein

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Translation Process Protein -> DCC Protein

DCC Protein Definition

Isolated as a gene in a region frequently deleted in colorectal carcinomas, the DCC gene encodes DCC Protein, which has sequence similarity to cell adhesion molecules such as N-CAM and may participate with other proteins in cell-cell and cell-matrix interactions. It is a transmembrane protein of the immunoglobulin superfamily, is expressed on spinal commissural axons and possesses netrin-1-binding activity. Knockout studies in mice failed to support a tumor-suppressor function for DCC in the mouse, but were consistent with the hypothesis that DCC is a component of the receptor for netrin-1, a neuronal chemoattractant. (from OMIM)

DCC Protein Synonyms

DCC Protein, CRC18, DCC, Deleted in Colorectal Carcinoma Protein

DCC Protein

DCC Protein Definition

DCC Protein Synonyms

Terms in DCC Protein category