DEAD-H Box Protein-16
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DEAD-H Box Protein-16 Definition
Encoded by human DDX16 Gene (DEAD/H Subfamily, member 16), ubiquitous 1041-amino acid 119.3-kD nuclear DEAD/H Box Protein 16 is a functional homolog of the Prp8/cdc28 cell cycle progression protein (S. pombe), similar to DEAH box proteins that act as splicing factors. DBP2 is a probable ATP-binding RNA helicase involved in pre-mRNA splicing. DEAD box proteins, characterized by a conserved Asp-Glu-Ala-Asp (DEAD) motif, are putative RNA helicases that alter RNA secondary structure and influence translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on distribution, some family members may be involved in embryogenesis, spermatogenesis, and cellular growth and division. (from LocusLink, Swiss-Prot, OMIM, and NCI)
DEAD-H Box Protein-16 Synonyms
DEAD/H Box Protein 16, ATP-Dependent RNA Helicase 3, DBP2, DDX16, DDX16 Protein, DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 16, DEAD/H Box 16, DEAH-Box Protein 16, DEAH-Box Protein 2, PRP8 Homolog, Putative Pre-mRNA Splicing Factor RNA Helicase
Terms in DEAD-H Box Protein-16 category
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