Cancer Terms

DNA Interstrand Cross-Link Repair

Cancer Terms -> Biological Process -> Subcellular Process -> Biochemical Process -> DNA Maintenance Process -> DNA Maintenance -> DNA Repair -> DNA Interstrand Cross-Link Repair

DNA Interstrand Cross-Link Repair Definition

DNA interstrand cross-links (ICLs) are very toxic to dividing cells, because they induce mutations, chromosomal rearrangements and cell death. A number of multi-step DNA repair pathways including nucleotide excision repair, homologous recombination and post-replication/translesion repair all impinge on their repair.

DNA Interstrand Cross-Link Repair Synonyms

DNA Interstrand Cross-Link Repair, Repair of DNA Interstrand Cross-Links

Terms in DNA Interstrand Cross-Link Repair category



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