Cancer Terms

DNA Mismatch Repair Protein-MLH1

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> DNA Repair Protein -> DNA Mismatch Repair Protein-MLH1

DNA Mismatch Repair Protein-MLH1 Definition

MLH1 protein is a DNA-binding, DNA-mismatch repair protein, of the MutL/HexB family, that dimerizes with PMS2 or MLH3. MLH1 is part of the multi-subunit BASC repair complex containing ATM, BLM, MSH2, MSH6, BRCA1, the RAD50/MRE11/NBS1 complex, and the RFC1/RFC2/RFC4 complex. MLH1 is homologous to MutL, which hydrolyzes ATP. (from OMIM 120436 and NCI)

DNA Mismatch Repair Protein-MLH1 Synonyms

DNA Mismatch Repair Protein MLH1, COCA2, FCC2, HNPCC, HNPCC2, MGC5172, MLH1, MLH1 Gene Product, MLH1 Protein, MUTL Protein Homolog 1, Mismatch DNA Repair Protein MLH1, Mismatch Repair Protein MLH1, hMLH1 Protein

Terms in DNA Mismatch Repair Protein-MLH1 category



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