Deoxycytidine Kinase
Cancer Terms ->
Gene Product ->
Protein ->
Protein Organized by Function ->
Enzyme ->
Transferase ->
Phosphotransferase ->
Kinase -> Deoxycytidine Kinase
Deoxycytidine Kinase Definition
Deoxycytidine Kinase, encoded by the DCK gene, is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. (from LocusLink)
Deoxycytidine Kinase Synonyms
Deoxycytidine Kinase, 2'-Deoxycytidine Kinase, ARA-C Kinase, DCK, EC 2.7.1.74
Terms in Deoxycytidine Kinase category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.