Dexverapamil
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Calcium Channel Blocker -> Dexverapamil
Dexverapamil Definition
The R-enantiomer of the calcium channel blocker verapamil. Dexverapamil competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1), thereby potentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. This agent exhibits decreased calcium antagonistic activity and toxicity compared to racemic verapamil. (NCI04)
Dexverapamil Synonyms
Dexverapamil, DEXVERAPAMIL, R Verapamil, R-Verapamil, R-Verapamil Hydrochloride
Terms in Dexverapamil category
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