Cancer Terms

Dexverapamil

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Agent Affecting Cardiovascular System -> Antihypertensive Agent -> Calcium Channel Blocker -> Dexverapamil

Dexverapamil Definition

The R-enantiomer of the calcium channel blocker verapamil. Dexverapamil competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1), thereby potentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. This agent exhibits decreased calcium antagonistic activity and toxicity compared to racemic verapamil. (NCI04)

Dexverapamil Synonyms

Dexverapamil, DEXVERAPAMIL, R Verapamil, R-Verapamil, R-Verapamil Hydrochloride

Terms in Dexverapamil category



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