Diphtheria Toxin Receptor
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Epidermal Growth Factor Superfamily Protein -> Diphtheria Toxin Receptor
Diphtheria Toxin Receptor Definition
Diphtheria Toxin Receptor, encoded by the human DTR gene, is a heparin-binding EGF-like growth factor. It is mitogenic for fibroblasts and smooth muscle and may be involved in macrophage-mediated cellular proliferation. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. This mature type I membrane protein is released into the extracellular space and probably binds to a receptor. (From LocusLink, Swiss-Prot and NCI)
Diphtheria Toxin Receptor Synonyms
Diphtheria Toxin Receptor, DT-R, DTR, DTR Protein, DTS, Diphtheria Toxin Sensitivity, HB-EGF, HBEGF, HEGFL, Heparin-Binding EGF-Like Growth Factor
Terms in Diphtheria Toxin Receptor category
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