Dopamine Receptor-D2

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Ligand Binding Protein -> Receptor -> Cell Surface Receptor -> G Protein-Coupled Receptor -> Dopamine Receptor -> Dopamine Receptor-D2

Dopamine Receptor-D2 Definition

Neurotransmission mediated by the Dopamine D2 Receptor (DRD2) plays a key role in the control of movement, in reward and reinforcement mechanisms in psychiatric disorders, and in the neuromodulation of appetitive behaviors. Acting through D2 dopamine receptors, dopamine specifically inhibits the vascular permeabilizing and angiogenic activities of VEGF by inducing endocytosis of VEGF receptor 2, preventing VEGF binding, receptor phosphorylation, and signaling.

Dopamine Receptor-D2 Synonyms

Dopamine Receptor D2, DRD2, DRD2 Receptor, Dopamine D2 Receptor

Terms in Dopamine Receptor-D2 category

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