Dual Specificity Phosphatase-3
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Dual-Specificity Phosphoprotein Phosphatase -> Dual Specificity Phosphatase-3
Dual Specificity Phosphatase-3 Definition
Encoded by human DUSP3 Gene, 185-amino acid 20.5 kD conserved VH1-Related Phosphatase is a non-receptor member of the dual specificity protein phosphatase subfamily (Protein-Tyrosine Phosphatase Family) that inactivates target substrates by dephosphorylating phosphotyrosine and phosphoserine/threonine residues. Negative regulators of MAPK/ERK, SAPK/JNK, and p38 members associated with cellular proliferation and differentiation, dual specificity phosphatases show different tissue distributions and subcellular locations, distinct substrate specificities for MAP kinases, and different modes of induction by extracellular stimuli. (from Swiss-Prot, OMIM, and NCI)
Dual Specificity Phosphatase-3 Synonyms
Dual Specificity Phosphatase 3, DUSP3, Dual Specificity Protein Phosphatase 3, Dual Specificity Protein Phosphatase VHR, EC 3.1.3.16, EC 3.1.3.48, Serine/Threonine Specific Protein Phosphatase, VH1-Related Phosphatase, Vaccinia Virus Phosphatase VH1-Related
Terms in Dual Specificity Phosphatase-3 category
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