E7820
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Endothelial-Specific Integrin-Survival Signaling Inhibitor -> E7820
E7820 Definition
A small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2 leads to an inhibition of cell-cell interactions, endothelial cell-matrix interactions, vascular endothelial cell proliferation and angiogenesis.
E7820 Synonyms
E7820
Terms in E7820 category
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