Cancer Terms

EMS1 wt Allele

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> EMS1 Gene -> EMS1 wt Allele

EMS1 wt Allele Definition

Human CTTN wild-type allele is located within 11q13 and is approximately 38 kb in length. This allele, which encodes Src substrate cortactin protein, plays a role in regulating the interactions between components of adherens-type junctions and in organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. Aberrant regulation of this gene contributes to tumor cell invasion and metastasis, and it is overexpressed in breast cancer and squamous cell carcinomas of the head and neck.

EMS1 wt Allele Synonyms

CTTN wt Allele, Cortactin wt Allele, EMS1

Terms in EMS1 wt Allele category



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