ERG wt Allele

Cancer Terms -> Gene -> Transcription Factor Gene -> ETS Family Gene -> ERG Gene -> ERG wt Allele

ERG wt Allele Definition

Human ERG wild-type allele is located in the vicinity of 21q22.3 and is approximately 280 kb in length. This allele, which encodes transcriptional regulator ERG protein, is involved in both the regulation of RNA polymerase II-directed transcription and the modification of local chromatin structure. Acute myelogenous leukemia of the subtype M2 is linked to the chromosomal translocation t(8;21)(q22;q22), which involves this gene and the EWSR1 gene. Human myeloid leukemia is linked to the chromosomal translocation t(16;21)(p11;q22) of this gene with the FUS gene.

ERG wt Allele Synonyms

ERG wt Allele, ERG, Early Response Gene, v-ETS Erythroblastosis Virus E26 Oncogene Like (Avian) wt Allele

ERG wt Allele

ERG wt Allele Definition

ERG wt Allele Synonyms

Terms in ERG wt Allele category