ETS Family Gene

Cancer Terms -> Gene -> Transcription Factor Gene -> ETS Family Gene

ETS Family Gene Definition

The Ets family of transcription factors includes nuclear phosphoproteins that are involved in cell proliferation, differentiation and oncogenic transformation. The family is defined by a conserved DNA-binding domain (the ETS-DBD), which forms a highly conserved, winged, helix-turn-helix structural motif. As targets of the Ras-MAPK signaling pathway, Ets proteins function as critical nuclear integrators of ubiquitous signaling cascades. To direct signals to specific target genes, ETS proteins interact with other transcription factors that determine the binding specificity of ETS proteins to RAS-response elements in target genes.

ETS Family Gene Synonyms

ETS Family Gene, ETS Family Proto-Oncogenes

Terms in ETS Family Gene category

ELK1 Gene
ELK3 Gene
ERG Gene
ETS1 Gene
ETS2 Gene
ETV1 Gene
ETV3 Gene
ETV4 Gene
ETV6 Gene
FLI1 Gene
SPI1 Gene

---

Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.