Eculizumab
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Monoclonal Antibody -> Eculizumab
Eculizumab Definition
A human monoclonal antibody directed against terminal complement protein C5. Eculizumab binds to terminal complement protein C5, thereby blocking C5 cleavage into pro-inflammatory components and blocking the complement-mediated destruction of paroxysmal nocturnal hemoglobinuria (PNH) red blood cells. (NCI05)
Eculizumab Synonyms
Eculizumab, Alexion, ECULIZUMAB, Monoclonal antibody 5G1.1, Soliris, h5G1.1
Terms in Eculizumab category
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