Elongation Factor-1D
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Elongation Factor-1D Definition
Encoded by human EEF1D Gene (EF1Beta/EF1Delta Family), 281-aa 31-kDa Elongation Factor 1D is a subunit of heterotrimeric Elongation Factor 1 (containing alpha/beta/gamma or alpha/delta/gamma subunits). Composed of an alpha subunit nucleotide binding domain and a beta/gamma subunit nucleotide exchange complex, Elongation Factor 1 is responsible for delivery of aminoacyl tRNAs to the ribosome. The homologous guanine nucleotide exchange factor EF-1-delta and EF-1-beta subunits stimulate GDP/GTP exchange bound to EF-1-alpha; phosphorylation affects the GDP/GTP exchange rate. EEF1D may interact with HIV-1 Tat and repress host-cell mRNA translation. (NCI)
Elongation Factor-1D Synonyms
Elongation Factor 1D, Antigen NY-CO-4, EEF1D, EF-1-Delta, Elongation Factor-1-Delta, Eukaryotic Translation Elongation Factor 1 Delta, Guanine Nucleotide Exchange Protein
Terms in Elongation Factor-1D category
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