Eltrombopag
Cancer Terms ->
Drugs and Chemicals ->
Pharmacologic Substance ->
Agent Affecting Blood And Body Fluid -> Eltrombopag
Eltrombopag Definition
The orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production.
Eltrombopag Synonyms
Eltrombopag Olamine, ELTROMBOPAG OLAMINE, Promacta, SB-497116-GR
Terms in Eltrombopag category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.