Endoribonuclease Dicer
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Rnase-III Family Protein -> Endoribonuclease Dicer
Endoribonuclease Dicer Definition
Endoribonuclease Dicer, encoded by the human DICER1 gene, possesses an RNA helicase motif, containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. It is required by the RNA interference in cleaving double-stranded RNA as well as small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. The 21 to 23 bp double-stranded RNAs (siRNAs) generated target the selective destruction of homologous RNAs. (From OMIM, Swiss-Port, and NCI)
Endoribonuclease Dicer Synonyms
Endoribonuclease Dicer, DICER1, DICER1 Protein, Dcr-1 Homolog, Dicer, EC 3.1.26.-, HERNA, Helicase with RNase Motif, Helicase-MOI, Homolog of Drosophila Dicer, K12H4.8-Like, KIAA0928
Terms in Endoribonuclease Dicer category
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