Erbstatin Analog
Cancer Terms ->
Drugs and Chemicals ->
Pharmacologic Substance ->
Enzyme Inhibitor ->
Protein Kinase Inhibitor ->
Tyrosine Kinase Inhibitor -> Erbstatin Analog
Erbstatin Analog Definition
A cell-permeable analog of erbstatin, a compound isolated from Streptomyces that inhibits the autophosphorylation of epidermal growth factor receptor. Erbstatin analogue competitively inhibits epidermal growth factor receptor-associated tyrosine kinase, inhibiting the activation of v-abl tyrosine kinase. In addition, this agent has induced apoptosis in mouse thymocytes and inhibits the G2/M phase of the cell cycle. (NCI)
Erbstatin Analog Synonyms
Methyl 2,5-dihydroxycinnamate, 3-(2,5-Dihydroxyphenyl)-2-propenoic Acid Methyl Ester, ALX-270-098, Methyl-2,5-dihydroxycinnamate
Terms in Erbstatin Analog category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.