Erlotinib
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Erlotinib Definition
The hydrochloride salt of a quinazoline derivative with antineoplastic properties. Competing with adenosine triphosphate, erlotinib reversibly binds to the intracellular catalytic domain of epidermal growth factor receptor (EGFR) tyrosine kinase, thereby reversibly inhibiting EGFR phosphorylation and blocking the signal transduction events and tumorigenic effects associated with EGFR activation.
Erlotinib Synonyms
Erlotinib Hydrochloride, CP-358,774, Cp-358,774, ERLOTINIB HYDROCHLORIDE, N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride, OSI-774, Tarceva
Terms in Erlotinib category
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