Esomeprazole Magnesium
Cancer Terms ->
Drugs and Chemicals ->
Pharmacologic Substance ->
Agent Affecting Digestive System Or Metabolism ->
Anti-ulcer Agent ->
Proton Pump Inhibitor -> Esomeprazole Magnesium
Esomeprazole Magnesium Definition
The magnesium salt of esomeprazole, the S-isomer of omeprazole, with gastric proton pump inhibitor activity. In the acidic compartment of parietal cells, esomeprazole is protonated and converted into the active achiral sulphenamide; the active sulphenamide forms one or more covalent disulfide bonds with the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting its activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production. H+/K+ ATPase is an integral membrane protein of the gastric parietal cell.
Esomeprazole Magnesium Synonyms
Esomeprazole Magnesium, ESOMEPRAZOLE MAGNESIUM, Nexium
Terms in Esomeprazole Magnesium category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.