Cancer Terms

Ethynyluracil Fluorouracil

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Antimetabolite -> Pyrimidine Antagonist -> Ethynyluracil Fluorouracil

Ethynyluracil Fluorouracil Definition

A combination tablet of ethynyluracil and fluorouracil. Fluorouracil is an antimetabolite fluoropyrimidine analog of the nucleoside pyrimidine with antineoplastic activity. Ethynyluracil is an orally-active fluoropyrimidine analog that inhibits dihydropyrimidine dehydrogenase, the rate-limiting enzyme that catabolizes and inactivates 5-fluorouracil in the liver. This may lead to an increase in the bioavailability and, effectiveness of fluorouracil.

Ethynyluracil Fluorouracil Synonyms

Eniluracil / 5-FU Combination Tablet, 776C85/5-FU, Ethynyluracil/Fluorouracil, GW776/5-FU, GW776/5-Fluorouracil

Terms in Ethynyluracil Fluorouracil category



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