Exostosin-2

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Transferase -> Glycosyltransferase -> Exostosin-2

Exostosin-2 Definition

EXT2 is a presumed tumor suppressor. EXT1 and EXT2 proteins are type II transmembrane glycoproteins that appear to form a heterooligomeric complex having glycosyl transferase activity involved in heparan sulfate polymerization. EXT2 interacts with a UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase. EXT1 and EXT2 proteins may play a role in modulation/diffusion of hedgehog signaling. EXT2 is involved in hereditary multiple exostoses. (from OMIM 133701 and NCI)

Exostosin-2 Synonyms

Exostosin-2, EXT2, Exostoses (multiple) 2

Terms in Exostosin-2 category

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